Journal article

On optimisation of Paganin's method for propagation-based X-ray phase-contrast imaging and tomography

TE Gureyev, DM Paganin, A Pakzad, HM Quiney

Journal of Microscopy | Published : 2026

Open access

Abstract

Paganin's method for image reconstruction in propagation-based phase-contrast X-ray imaging and tomography has enjoyed broad acceptance in recent years, with over one thousand publications citing its use. The present paper discusses approaches to optimisation of the method with respect to simple image quality metrics, such as signal-to-noise ratio and spatial resolution, as well as a reference-based metric corresponding to the relative mean squared difference between the reconstructed image and the ‘ground truth’ image that would be obtained in a setup with perfect spatial resolution and no noise. The problem of optimisation of the intrinsic regularisation parameter of Paganin's method with ..

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