Evaluation of Ultrasound Shear Wave Elastography (SWE) and Attenuation Imaging (ATI) for the Assessment of Hepatic Fibrosis and Steatosis—A Prospective Comparison With MRI Liver Elastography and Proton Density Fat Fraction (PDFF)

Abstract

Introduction: To assess competing US techniques in evaluation of chronic liver disease, we performed a study to determine the diagnostic accuracy of 2D-shear wave elastography (2D-SWE) and attenuation imaging (ATI) compared with more established methods of point shear wave elastography (pSWE) and visual B-mode grading of hepatic steatosis. Magnetic resonance elastography (MRE) and proton density fat fraction (MR-PDFF) were used as respective reference standards. Methods: Fifty-five patients underwent same-day liver ultrasound (conventional B-mode, pSWE, 2D-SWE, and ATI) and 3 T MRI (MRE and MR-PDFF). Diagnostic performance for steatosis (mild, moderate, severe) and fibrosis (≥ F2, ≥ F3, and ..