Journal article
Predicting recurrence patterns and outcomes following resection of pancreatic ductal adenocarcinoma: a contemporary real-world data cohort study
Eden Mane, Mark Tacey, Ben Loveday, Jeremy Shapiro, Michael Michael, Brett Knowles, Sue-Anne McLachlan, Rachel Wong, Rob Zielinski, Mehrdad Nikfarjam, Amitesh Roy, Fiona Day, Vanessa Durandt, Matthew Burge, Susan Caird, Cheng Ean Chee, David Tai, Belinda Lee
Annals of Medicine & Surgery | Ovid Technologies (Wolters Kluwer Health) | Published : 2026
Abstract
Introduction: The prognosis in pancreatic ductal adenocarcinoma (PDAC) remains poor with 2-year recurrence rates around 80% despite curative-intent surgery. This study evaluated factors associated with early recurrence in a contemporary, multi-center, Australasian population. A better understanding of patients at risk of early recurrence (ER) could improve selection of operative candidates. Methods: De-identified data were extracted from 23 hospitals participating in the PURPLE pancreatic cancer registry between 2016 and 2024. Clinicopathological features, treatment, recurrence patterns, and sur..
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