Journal article

Toward a fully wireless endovascular neural interface: Evaluating power transfer efficacy

YD Tai, J Villalobos, N Wickramasinghe, B Widdicombe, RR Unnithan, DB Grayden, SE John

Plos One | Published : 2026

Open access

Abstract

Background Endovascular neural interfaces (ENIs) offer a minimally invasive approach for neural stimulation and recording without the need for open brain surgery. However, current generation devices have long transvascular wires from the implant site to the chest. Eliminating these wires will unlock clinical usability, including lowering infection risk from transvascular wires, reducing the risk of thrombosis from altered hemodynamics, and improving mechanical reliability. However, removing these transvascular wires would require efficient power transfer across the skull and tissue while meeting specific absorption rate (SAR) limits, which is a significant challenge in the field. Objective T..

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