Wavelength and Polarization Multiplexed Nonlocal Metasurface for Quantitative Phase Microscopy

Abstract

Imaging transparent samples remains an ongoing challenge in the study of unstained biological cells and material samples. Widely used methods trade off system complexity, cost and bulk, computational efficiency, and information content. Here, a nonlocal metasurface located in the object plane is demonstrated for obtaining single-shot, low-noise differential phase contrast images visualizing phase gradients along orthogonal directions in a sample obtained at wavelengths of 613 and 656 nm. These images are sufficient to calculate the quantitative phase introduced into the transmitted optical field by the sample, with experiments showing the recovered phase generated by a spatial light modulato..