Anopheles salivary antibody biomarker outcomes to assess the effectiveness of topical repellent in Southeast Myanmar

Ellen A Kearney; Paul A Agius; Katherine O’Flaherty; Win Han Oo; Julia C Cutts; Win Htike; Daniela Da Silva Gonçalves; Aung Thi; Kyaw Zayar Aung; Htin Kyaw Thu; Myat Mon Thein; Nyi Nyi Zaw; Wai Yan Min Htay; Aung Paing Soe; Julie A Simpson; Freya JI Fowkes

Journal article

Anopheles salivary antibody biomarker outcomes to assess the effectiveness of topical repellent in Southeast Myanmar

Ellen A Kearney, Paul A Agius, Katherine O’Flaherty, Win Han Oo, Julia C Cutts, Win Htike, Daniela Da Silva Gonçalves, Aung Thi, Kyaw Zayar Aung, Htin Kyaw Thu, Myat Mon Thein, Nyi Nyi Zaw, Wai Yan Min Htay, Aung Paing Soe, Julie A Simpson, Freya JI Fowkes

Parasites & Vectors | Springer Science and Business Media LLC | Published : 2026

DOI: 10.1186/s13071-026-07694-6

Open access

Abstract

Abstract Background Measurement of human antibodies against Anopheles salivary proteins that are injected during mosquito bites may serve as biomarkers of mosquito biting exposure. These biomarkers have been suggested as useful outcomes in trials of vector-control intervention effectiveness; however, studies to-date have been largely descriptive and do not directly quantify the instantaneous nor cumulative effects of the intervention on antibody outcomes. In this study, we sought to explore the use of a serological biomarker of Anopheles ..

View full abstract