The genetics of age-related macular degeneration

Abstract

Aim: To review the genetics of age-related macular degeneration (AMD). The pathogenesis of AMD, the leading cause of severe visual disability and blindness in our community, remains unknown. However, AMD is regarded as a genetic disease where family history of AMD is a significant risk factor for the disease. Understanding the genetic factors associated with AMD offers the greatest chance for understanding the underlying disease processes. Methods: Through a review of the literature and the use of original research findings, the current knowledge of the genetics of AMD is explored. Conclusion: AMD is increasing in prevalence and remains a major challenge for eye heath providers. Finding the ..