Journal article

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor

K Mishima, TG Johns, RB Luwor, AM Scott, E Stockert, AA Jungbluth, XD Ji, P Suvarna, JR Voland, LJ Old, HJS Huang, WK Cavenee

Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2001

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Keywords

Antibodies, Monoclonal
Brain Neoplasms
Inhibition
Erbb Receptors
Apoptosis
Doxorubicin
Oncology
Xenograft Model Antitumor Assays
Down-Regulation
Cell Division
Glioblastoma
Antineoplastic Agents
Therapy
Human-Breast
Humans
Neovascularization, Pathologic
Animals
Bcl-X Protein
Survival Rate
in Situ Nick-End Labeling
Tumorigenicity
Expression
Phosphorylation
Science & Technology
Mice
Tumor Cells, Cultured
Combination
Common
Blotting, Western
Mice, Nude
Survival Analysis
Mutation
Gene Expression Regulation, Neoplastic
Cells
Treatment Outcome
Proto-Oncogene Proteins C-Bcl-2
Protein
Transplantation, Heterologous
Life Sciences & Biomedicine