Journal article

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor

K Mishima, TG Johns, RB Luwor, AM Scott, E Stockert, AA Jungbluth, XD Ji, P Suvarna, JR Voland, LJ Old, HJS Huang, WK Cavenee

Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2001

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Keywords

Survival Analysis
Proto-Oncogene Proteins C-Bcl-2
Tumor Cells, Cultured
Antineoplastic Agents
Common
Erbb Receptors
Human-Breast
Cells
Survival Rate
Antibodies, Monoclonal
Doxorubicin
Xenograft Model Antitumor Assays
Cell Division
Inhibition
Neovascularization, Pathologic
in Situ Nick-End Labeling
Brain Neoplasms
Down-Regulation
Mice, Nude
Humans
Transplantation, Heterologous
Combination
Gene Expression Regulation, Neoplastic
Therapy
Receptor, Epidermal Growth Factor
Oncology
Science & Technology
Mice
Protein
Apoptosis
Treatment Outcome
Animals
Glioblastoma
Mutation
Phosphorylation
Life Sciences & Biomedicine
Tumorigenicity
Blotting, Western
Expression
Bcl-X Protein