Journal article

Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor

K Mishima, TG Johns, RB Luwor, AM Scott, E Stockert, AA Jungbluth, XD Ji, P Suvarna, JR Voland, LJ Old, HJS Huang, WK Cavenee

Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2001

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Keywords

Animals
Apoptosis
Transplantation, Heterologous
Treatment Outcome
Cells
Phosphorylation
in Situ Nick-End Labeling
Proto-Oncogene Proteins C-Bcl-2
Mutation
Brain-Tumors
Oncology
Combination
Brain Neoplasms
Antineoplastic Agents
Life Sciences & Biomedicine
Down-Regulation
Doxorubicin
Blotting, Western
Mice, Nude
Confers Enhanced Tumorigenicity
Science & Technology
Humans
Neovascularization, Pathologic
Xenograft Model Antitumor Assays
Survival Analysis
Human Gliomas
Tumor Cells, Cultured
Mice
Cell Division
Erbb Receptors
Gene Expression Regulation, Neoplastic
Breast-Cancer Xenografts
Survival Rate
Common
Antibodies, Monoclonal
Bcl-X Protein
Therapy
Glioblastoma
Expression
Receptor, Epidermal Growth Factor