Botulinum toxin type A in the management of equinus in children with cerebral palsy: An evidence-based economic evaluation

Abstract

Introduction The aim of this study was to compare two methods of conservative management of calf spasticity and equinus gait - intramuscular injection of botulinum toxin type A (BTX-A) and serial casting. An economic evaluation framework was adopted to assess whether BTX-A offers value for money in the management of equinus gait due to calf spasticity in children with cerebral palsy. Short- to mediumterm health care costs and outcomes were estimated for the comparison. This study was embarked upon to provide clinical and economic data as part of an application to the Pharmaceutical Benefits Advisory Committee (PBAC) for the reimbursement of BOTOX® by the Australian Commonwealth Government. T..