Journal article

Continuous distending pressure for respiratory distress in preterm infants

JJ Ho, P Subramaniam, PG Davis

Cochrane Database of Systematic Reviews | WILEY | Published : 2015

Abstract

Background: Respiratory distress syndrome (RDS) is the single most important cause of morbidity and mortality in preterm infants. In infants with progressive respiratory insufficiency, intermittent positive pressure ventilation (IPPV) with surfactant is the standard treatment for the condition, but it is invasive, potentially resulting in airway and lung injury. Continuous distending pressure (CDP) has been used for the prevention and treatment of RDS, as well as for the prevention of apnoea, and in weaning from IPPV. Its use in the treatment of RDS might reduce the need for IPPV and its sequelae. Objectives: To determine the effect of continuous distending pressure (CDP) on the need for IPP..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

Internal sourcesPenang Medical College, Malaysia.Centre for Perinatal Health Services Research, University of Sydney, Australia.Royal Womens Hospital, Melbourne, Australia.Wanganui Hospital, New Zealand.Neonatal Unit, Royal Prince Alfred Hospital, Sydney, Australia.External sourcesEunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA.Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN275201100016C