Metalloenzyme-like activity of Alzheimer's disease beta-amyloid - Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2

C Opazo; XD Huang; RA Cherny; RD Moir; AE Roher; AR White; R Cappai; CL Masters; RE Tanzi; NC Inestrosa; AI Bush

Journal article

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid - Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2

C Opazo, XD Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, CL Masters, RE Tanzi, NC Inestrosa, AI Bush

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2002

DOI: 10.1074/jbc.M206428200

University of Melbourne Researchers

Ashley Bush Author Florey Department of Neuroscience and Mental Health

Colin Masters Author Florey Department of Neuroscience and Mental Health

Roberto Cappai Author Biochemistry and Pharmacology

Carlos Opazo Martinez Author Florey Department of Neuroscience and Mental Health

Robert Cherny Author Clinical Pathology

Grants

Awarded by NIA NIH HHS

Awarded by NIMH NIH HHS

Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH

Awarded by NATIONAL INSTITUTE ON AGING

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Keywords

Biochemistry & Molecular Biology

Amyloid Beta-Peptides

Neurofibrillary Tangles

Life Sciences & Biomedicine

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid - Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2

University of Melbourne Researchers

Grants

Citation metrics

Keywords

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