Journal article

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells

AA Ruefli, D Bernhard, KM Tainton, R Kofler, MJ Smyth, RW Johnstone

International Journal of Cancer | WILEY | Published : 2002

DOI: 10.1002/ijc.10327

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Keywords

Multidrug Resistance
Colonic Neoplasms
P-Glycoprotein
Hydroxamic Acids
Caspases
Atp Binding Cassette Transporter, Subfamily B, Member 1
Vincristine
Leukemia, T-Cell
Chemotherapy
Cell Cycle
Histone Deacetylase Inhibitor
Drug Resistance, Multiple
Histone Deacetylase
Caspase Activation
Leukemia-Cells
Protein
Enzyme Inhibitors
Potent Inducers
Leukemia, Erythroblastic, Acute
Pathways
Cytochrome C Group
Cell Death
Reactive Oxygen Species
Cytochrome-C
Poly(adp-Ribose) Polymerases
Humans
Bcl-2
Histones
Tumor Cells, Cultured
Science & Technology
Apoptosis
Differentiation
Antineoplastic Agents
Life Sciences & Biomedicine
Chromium Radioisotopes
Gene Expression
Caspase 3
Histone Deacetylase Inhibitors
Oncology
Vorinostat
Enzyme Activation