Journal article

Functional significance of the perforin/granzyme cell death pathway

JA Trapani, MJ Smyth

Nature Reviews Immunology | NATURE PUBLISHING GROUP | Published : 2002

DOI: 10.1038/nri911

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Keywords

Killer Cells, Natural
Immunology
Apoptosis
Pore Forming Cytotoxic Proteins
Models, Immunological
Granule Exocytosis
Serine Endopeptidases
Mediated Cytotoxicity
Mice, Mutant Strains
Infection
Granzyme A-Deficient
Membrane Glycoproteins
Autoimmunity
Humans
Natural-Killer-Cells
Perforin
T-Lymphocytes, Cytotoxic
Apoptosis-Inducing Ligand
Versus-Host-Disease
In-Vivo
Mice
Life Sciences & Biomedicine
Fas Ligand
Infections
Graft Vs Host Disease
Science & Technology
Cd8(+) T-Cells
Histiocytosis, Non-Langerhans-Cell
Animals
Cytochrome-C Release