Journal article

Functional significance of the perforin/granzyme cell death pathway

JA Trapani, MJ Smyth

Nature Reviews Immunology | NATURE PUBLISHING GROUP | Published : 2002

DOI: 10.1038/nri911

Citation metrics

670Web of Science
716Scopus

Keywords

Life Sciences & Biomedicine
Apoptosis-Inducing Ligand
Natural-Killer-Cells
Mice
Infection
Mice, Mutant Strains
Pore Forming Cytotoxic Proteins
Science & Technology
Graft Vs Host Disease
Perforin-Deficient Mice
Chronic Viral-Infection
Membrane Glycoproteins
Cd8(+) T-Cells
Perforin
Autoimmunity
Lymphocytic Choriomeningitis Virus
Immunology
Histiocytosis, Non-Langerhans-Cell
Models, Immunological
Versus-Host Disease
Humans
Nonobese Diabetic Mice
Killer Cells, Natural
Mediated Tumor Rejection
Animals
Serine Endopeptidases
T-Lymphocytes, Cytotoxic
Infections
Cytochrome-C Release
Apoptosis