Journal article

ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat

JL Wilkinson-Berka, DJ Kelly, SM Koerner, K Jaworski, B Davis, V Thallas, ME Cooper

Diabetes | AMER DIABETES ASSOC | Published : 2002

DOI: 10.2337/diabetes.51.11.3283

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Keywords

Kidney Cortex
Immunohistochemistry
Organ Size
Angiotensin-Ii
Vascular Dysfunction
Mesangial Expansion
Prevention
Injury
Apoptosis
Glycation End Products, Advanced
Body Weight
Glomerular Filtration Rate
Nitric Oxide Synthase
Gene-Expression
Rats
Extracellular-Matrix
Life Sciences & Biomedicine
Blood Pressure
Nitric-Oxide
End-Product Formation
Animals, Genetically Modified
Diabetes Mellitus, Experimental
Diabetic Nephropathies
Enzyme Inhibitors
Amides
Animals
Science & Technology
Rats, Mutant Strains
Endocrinology & Metabolism
Hydrazines
Guanidines