Journal article

Tumor-mediated apoptosis of cancer-specific T lymphocytes - Reversing the "kiss of death"?

JA Trapani

CANCER CELL | CELL PRESS | Published : 2002


Recent studies have provided evidence that some cancers can aberrantly express molecules capable of inducing apoptosis of tumor-reactive lymphocytes. Several other potential tumor escape mechanisms that can block the cytotoxic pathways activated by killer T cells have also been proposed.