Journal article

Allosteric binding sites on cell-surface receptors: Novel targets for drug discovery

A Christopoulos

Nature Reviews Drug Discovery | NATURE PUBLISHING GROUP | Published : 2002

DOI: 10.1038/nrd746

University of Melbourne Researchers

Arthur Christopoulos Author Biochemistry and Pharmacology

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Keywords

Endothelin Eta Receptors

Receptors, Cell Surface

Biotechnology & Applied Microbiology

Positive Cooperative Interactions

Antagonist Binding

Protein-Coupled Receptors

Amiloride Analogs

Life Sciences & Biomedicine

Pharmaceutical Preparations

Allosteric Site

Muscarinic Receptors

Nicotinic Acetylcholine-Receptors

Pharmacology & Pharmacy

Structure-Activity Relationship

Ternary Complex Model

Science & Technology