Journal article

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

NR Martinez, P Augstein, AK Moustakas, GK Papadopoulos, S Gregori, L Adorini, DC Jackson, LC Harrison

Journal of Clinical Investigation | AMER SOC CLINICAL INVESTIGATION INC | Published : 2003

DOI: 10.1172/JCI200317166

University of Melbourne Researchers

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Keywords

Peptides
Protein Structure, Tertiary
Beta-Cell Function
T-Cells
Oral Insulin
Molecule
Disease
Spleen
Tolerance
Mice, Inbred Nod
Myelin Basic-Protein
Diabetes Mellitus, Type 1
Mhc Class-I
Female
Models, Molecular
Medicine, Research & Experimental
Autoantigen
Research & Experimental Medicine
Life Sciences & Biomedicine
Protein Binding
Adoptive Transfer
Animals
Male
Nod Mice
Mice
T-Lymphocytes, Cytotoxic
Science & Technology
Administration, Intranasal
Cells, Cultured
Epitopes
Humans
Proinsulin