Journal article

Anterior temporal changes on MR images of children with hippocampal sclerosis: An effect of seizures on the immature brain?

LA Mitchell, AS Harvey, LT Coleman, SA Mandelstam, GD Jackson

American Journal of Neuroradiology | AMER SOC NEURORADIOLOGY | Published : 2003


BACKGROUND AND PURPOSE: Ipsilateral loss of anterior temporal gray-white matter definition, due mainly to white matter signal intensity abnormality, is frequently seen on MR images of patients with hippocampal sclerosis. Our aim was to determine the prevalence and clinical correlations of these anterior temporal changes in pediatric cases of hippocampal sclerosis and to determine whether cumulative damage from seizures is important for their development. METHODS: We reviewed the MR images and clinical details of 54 children (age range, 1.5-19 years) with typical hippocampal sclerosis. Specific imaging features noted included hippocampal sclerosis, anterior temporal changes, anterior temporal..

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