Journal article

Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-beta 1 integrin complex in colon cancer cells

N Ahmed, K Oliva, Y Wang, M Quinn, G Rice

British Journal of Cancer | NATURE PUBLISHING GROUP | Published : 2003

DOI: 10.1038/sj.bjc.6601098

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Keywords

Neoplasm Metastasis
Oncology
Urokinase Plasminogen Activator Receptor
Receptors, Urokinase Plasminogen Activator
Down-Regulation
Membrane Glycoproteins
Invasion
Adhesion
Colon Cancer
Matrix Degradation
In-Vivo
Receptors, Cell Surface
Neoplasm Invasiveness
Antigens, Cd29
Human Carcinoma
Colonic Neoplasms
Humans
Plasminogen Activation and Metastasis
Ovarian-Cancer
Science & Technology
Signal Transduction
Tumor-Growth
Tumor Cells, Cultured
Migration
Beta 1 Integrin
Alpha-V-Beta-6 Integrin
Mitogen-Activated Protein Kinases
Overexpression
Transfection
Mannose-Binding Lectins
Integrin Beta1
Life Sciences & Biomedicine