Journal article

Evaluation of use of recombinant Em18 and affinity-purified Em18 for serological differentiation of alveolar echinococcosis from cystic echinococcosis and other parasitic infections

N Xiao, W Mamuti, H Yamasaki, Y Sako, M Nakao, K Nakaya, B Gottstein, PM Schantz, MW Lightowlers, PS Craig, A Ito

Journal of Clinical Microbiology | AMER SOC MICROBIOLOGY | Published : 2003

Abstract

To further evaluate recombinant Em18 antigen (rEm18) for immunodiagnosis of human alveolar echinococcosis, 208 serum samples were examined by enzyme-linked immunosorbent assay (ELISA). To comparatively assess the results of rEm18-ELISA, ELISA and immunoblot analysis with two affinity-purified native antigens were also performed with 45 selected serum samples. The results indicate that rEm18 is highly useful for serodiagnosis.

University of Melbourne Researchers