Journal article
Electrical Remodeling of the Atria in Congestive Heart Failure
Prashanthan Sanders, Joseph B Morton, Neil C Davidson, Steven J Spence, Jitendra K Vohra, Paul B Sparks, Jonathan M Kalman
Circulation | Wolters Kluwer | Published : 2003
Abstract
BACKGROUND: Atrial fibrillation (AF) frequently complicates congestive heart failure (CHF). However, the electrophysiological substrate for AF in humans with CHF remains unknown. We evaluated the electrophysiological and electroanatomic characteristics of the atria in patients with CHF. METHODS AND RESULTS: Twenty-one patients (aged 53.7+/-13.6 years) with symptomatic CHF (left ventricular ejection fraction 25.5+/-6.0%) and 21 age-matched controls were studied. The following were evaluated: effective refractory periods (ERPs) from the high and low lateral right atrium (LRA), high septal right atrium, and distal coronary sinus (CS); conduction time along the CS and LRA; corrected sinus node r..
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