Detection of synchronous adenocarcinomas and multiple dysplastic polyps with F-18FDG positron emission tomography in a case of nonfamilial polyposis

Abstract

A 46-year-old man was examined for symptomatic anemia. Colonoscopy showed a stenosing carcinoma of the right ascending colon, a villous tumor of the rectum, and multiple (>100) polyps in the colon and rectum. An F-18 fluorodeoxyglucose (FDG) positron emission tomographic (PET) scan showed multiple foci of uptake throughout the colon. The presence of multiple metabolically active lesions throughout the colon resulted in a change to more radical surgery. A total proctocolectomy with radical lymphovascular mesenteric resection was performed. The surgical specimen revealed more than 160 polyps, a large cecal adenocarcinoma with transmural invasion, and microscopic involvement of 2 of 12 ileoceca..