Journal article

Topographic plasticity in primary visual cortex is mediated by local corticocortical connections

MB Calford, LL Wright, AB Metha, V Taglianetti

JOURNAL OF NEUROSCIENCE | SOC NEUROSCIENCE | Published : 2003

Abstract

The placement of monocular laser lesions in the adult cat retina produces a lesion projection zone (LPZ) in primary visual cortex (V1) in which the majority of neurons have a normally located receptive field (RF) for stimulation of the intact eye and an ectopically located RF (displaced to intact retina at the edge of the lesion) for stimulation of the lesioned eye. Animals that had such lesions for 14-85 d were studied under halothane and nitrous oxide anesthesia with conventional neurophysiological recording techniques and stimulation of moving light bars. Previous work suggested that a candidate source of input, which could account for the development of the ectopic RFs, was long-range ho..

View full abstract

University of Melbourne Researchers