Second line treatment for severe acute childhood asthma

Abstract

The choice of treatment for a child with severe acute asthma unresponsive to high dose inhaled bronchodilators and oral or intravenous corticosteroids is still the subject of debate. Although both salbutamol and aminophylline have been around for a long time and have been the subject of many studies, it is still not possible unreservedly to recommend one of these agents over the other as second line treatment.