Journal article

Rotavirus serotype G9P[8] and acute gastroenteritis outbreak in children, Northern Australia

C Kirkwood, N Bogdanovic-Sakran, G Barnes, R Bishop

EMERGING INFECTIOUS DISEASES | CENTER DISEASE CONTROL | Published : 2004

Abstract

During 2001, an outbreak of severe acute gastroenteritis swept through Central and northern Australia and caused serious disruption to health services. We tracked and characterized the rotavirus strain implicated in the outbreak. Comparison of the electropherotypes of outbreak samples suggested that one G9P[8] strain was likely responsible for the outbreak. Samples were obtained from geographically distinct regions of Australia where the epidemic had occurred. The outbreak strains showed identical nucleotide sequences in genes encoding three rotavirus proteins, VP7, VP8, and NSP4, but they were distinct from G9P[8] strains isolated in previous years. Several of the amino acid substitutions o..

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