Journal article

The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer

EM John, JL Hopper, JC Beck, JA Knight, SL Neuhausen, RT Senie, A Ziogas, IL Andrulis, H Anton-Culver, N Boyd, SS Buys, MB Daly, FP O'Malley, RM Santella, MC Southey, VL Venne, DJ Venter, DW West, AS Whittemore, D Seminara

Breast Cancer Research | BMC | Published : 2004


INTRODUCTION: The etiology of familial breast cancer is complex and involves genetic and environmental factors such as hormonal and lifestyle factors. Understanding familial aggregation is a key to understanding the causes of breast cancer and to facilitating the development of effective prevention and therapy. To address urgent research questions and to expedite the translation of research results to the clinical setting, the National Cancer Institute (USA) supported in 1995 the establishment of a novel research infrastructure, the Breast Cancer Family Registry, a collaboration of six academic and research institutions and their medical affiliates in the USA, Canada, and Australia. METHODS:..

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