Journal article

Genetically decreased spinal cord copper concentration prolongs life in a transgenic mouse model of amyotrophic lateral sclerosis

M Kiaei, AI Bush, BM Morrison, JH Morrison, RA Cherny, I Volitakis, MF Beal, JW Gordon

Journal of Neuroscience | SOC NEUROSCIENCE | Published : 2004

DOI: 10.1523/JNEUROSCI.2000-04.2004

Grants

Awarded by NIA NIH HHS

Citation metrics

44Web of Science
44Scopus

Keywords

Enzyme Induction
Male
Superoxide Dismutase-1
Biological Transport, Active
Disease
Motor-Neurons
Neurosciences
Amyotrophic Lateral Sclerosis
Spinal Cord
Mice, Mutant Strains
K-M
Motor Neuron
Amino Acid Substitution
Alleles
Phenotype
Sod1
Brain
Mice
Cu,zn-Superoxide Dismutase Mutant
Mitochondria
Copper
Brain Chemistry
Adenosine Triphosphatases
Animals
Crosses, Genetic
Als
Superoxide-Dismutase
Life Sciences & Biomedicine
Mice, Inbred C57bl
Nerve Tissue Proteins
Longevity
Science & Technology
Mice, Transgenic
Mutation, Missense
Superoxide Dismutase
Neurodegeneration
Copper-Transporting Atpases
Neurosciences & Neurology
Disease Models, Animal
Hydrogen-Peroxide
Female
Binding Sites
Cation Transport Proteins
Mottled/ Brindled