The role of thallium-201 and pentavalent dimercaptosuccinic acid for staging cartilaginous tumours.
Peter Fm Choong, Toshiyuki Kunisada, John Slavin, Stephen Schlicht, Rodney Hicks
Int Semin Surg Oncol | Published : 2004
INTRODUCTION: Heterogeneity of cartilage tumours may confound accurate diagnosis and grading resulting in under and over treatment. Improved preoperative assessment of malignancy and grade would be invaluable for developing a rational plan for treatment. We examined correlations between nuclear tracer avidity and malignancy grade in cartilage tumours. METHODS: Between 1996 and 2000, 92 consecutive patients with cartilaginous tumours (50 benign, 42 non-metastatic malignant) underwent nuclear scanning. Thallium-201 (TL-201) and pentavalent dimercaptosuccinic acid (DMSAV) were used as nuclear isotopes. Scanning with these agents was performed on separate days 48 hours apart. Static and SPECT im..View full abstract