Journal article

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution

GD Ciccotosto, D Tew, CC Curtain, D Smith, D Carrington, CL Masters, AI Bush, RA Cherny, R Cappai, KJ Barnham

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2004

DOI: 10.1074/jbc.M406465200

University of Melbourne Researchers

Joe Ciccotosto Author Pharmacology and Therapeutics

Kevin Barnham Author Florey Department of Neuroscience and Mental Health

Ashley Bush Author Florey Department of Neuroscience and Mental Health

Colin Masters Author Florey Department of Neuroscience and Mental Health

Roberto Cappai Author Pharmacology and Therapeutics

Citation metrics

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Keywords

Hydrogen Peroxide

Lipid Metabolism

Biochemistry & Molecular Biology

Circular Dichroism

Amyloid Beta-Peptides

Microscopy, Electron

Dose-Response Relationship, Drug

Cerebral Cortex

Long-Term Potentiation

Cells, Cultured

Radical Oxidative Stress

Hydrogen-Peroxide

Alzheimers-Disease

Protein Binding

Lipid-Peroxidation

Electron Spin Resonance Spectroscopy

Life Sciences & Biomedicine

Protein Structure, Secondary

Science & Technology

Protein Conformation

Soluble Oligomers