Journal article

APP intracellular domain is increased and soluble A beta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

AJ George, RMD Holsinger, CA McLean, KM Laughton, K Beyreuther, G Evin, CL Masters, QX Li

Neurobiology of Disease | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2004

DOI: 10.1016/j.nbd.2004.01.009

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Keywords

Female
Solubility
Protein Structure, Tertiary
Life Sciences & Biomedicine
Cholesterol, Dietary
Hypercholesterolemia
Terminal Fragment
Mice
Amyloid Precursor Protein
Alzheimer Disease
Transgenic Mouse
Secretase Cleavage
Cholesterol-Metabolism
In-Vivo
a Beta Amyloid
Human Brain
Apolipoprotein-E
Intracellular Fluid
Amyloid Beta-Peptides
Amyloid Beta-Protein Precursor
Alpha-Secretase
Cholesterol
Cerebrospinal-Fluid
Neurosciences
Neurosciences & Neurology
Mice, Transgenic
Aicd
Animals
Science & Technology
Controlled Trial