Journal article

APP intracellular domain is increased and soluble A beta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease

AJ George, RMD Holsinger, CA McLean, KM Laughton, K Beyreuther, G Evin, CL Masters, QX Li

Neurobiology of Disease | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2004

DOI: 10.1016/j.nbd.2004.01.009

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Keywords

Female
Science & Technology
Controlled Trial
Transgenic Mouse
Amyloid Beta-Protein Precursor
Aicd
Neurosciences & Neurology
Secretase Cleavage
Mice, Transgenic
Cholesterol-Metabolism
Hypercholesterolemia
Intracellular Fluid
In-Vivo
Solubility
Amyloid Precursor Protein
Cholesterol
Mice
Amyloid Beta-Peptides
Terminal Fragment
Apolipoprotein-E
Human Brain
Cerebrospinal-Fluid
Neurosciences
Cholesterol, Dietary
Protein Structure, Tertiary
Alzheimer Disease
Life Sciences & Biomedicine
Alpha-Secretase
a Beta Amyloid
Animals