Journal article

Population pharmacokinetics of sibrotuzumab, a novel therapeutic monoclonal antibody, in cancer patients

C Kloft, EU Graefe, P Tanswell, AM Scott, R Hofheinz, A Amelsberg, MO Karlsson

Investigational New Drugs | SPRINGER | Published : 2004

DOI: 10.1023/B:DRUG.0000006173.72210.1c

University of Melbourne Researchers

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Keywords

Humanized Monoclonal Antibody
Antibodies, Monoclonal
Growth
Pharmacology & Pharmacy
Clinical Trials, Phase I As Topic
Molecular-Cloning
Infusions, Intravenous
Oncology
Antibodies, Monoclonal, Humanized
Life Sciences & Biomedicine
Population Pharmacokinetics
Nonlinear Kinetics
Humans
Models, Biological
Metabolic Clearance Rate
Aged
Clinical Trials, Phase Ii As Topic
Sibrotuzumab
Science & Technology
Serine-Protease
Male
Aged, 80 and Over
Basiliximab
Colon-Cancer
Adult
Tumor Stroma
Middle Aged
Fibroblast Activation Protein
Generation
Immunotherapy
Neoplasms
Model
Female
Stromal Fibroblasts