Journal article

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

SA Bellingham, DK Lahiri, B Maloney, S La Fontaine, G Multhaup, J Camakaris

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2004

DOI: 10.1074/jbc.M400805200

University of Melbourne Researchers

Grants

Awarded by NIA NIH HHS

Awarded by NATIONAL INSTITUTE ON AGING

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Keywords

Recombinant Fusion Proteins
Down-Regulation
Humans
Plasmids
Menkes-Disease
Transport
Cation Transport Proteins
Copper-Transporting Atpases
Gene Deletion
P-Type Atpase
Science & Technology
Cells
Promoter Regions, Genetic
Iron
Transgenic Mice
Cells, Cultured
Beta-Galactosidase
Alzheimer Disease
Brain
Chloramphenicol O-Acetyltransferase
Animals
Genetic Vectors
Adenosine Triphosphatases
Promoter
Blotting, Northern
Macaca Mulatta
Amyloid Beta-Peptides
Transcriptional Activity
Rna, Messenger
Life Sciences & Biomedicine
Zinc
Fluorescent Antibody Technique, Indirect
Copper
Binding
Transfection
Peptides
Computational Biology
Reduction
Fibroblasts
Biochemistry & Molecular Biology