A controlled, prospective study of neuropsychological outcomes post parathyroidectomy in primary hyperparathyroid patients

Abstract

Background: There is an increasing number of primary hyperparathyroidism (PHPT) patients with neuropsychological or psychiatric symptoms. Many of these patients do not have osseous or renal complications to satisfy the criteria for parathyroidectomy according to the NIH guidelines. Objective: To assess whether there is any improvement in neuropsychological and mood symptoms following parathyroidectomy. Patients and Design: Twenty PHPT patients undergoing parathyroidectomy and 20 orthopaedic controls matched for age, gender and estimated intelligence were subjects to pre and postoperative assessment of cognition and mood with a mean surgery-retest interval of 3 months. Results: Using two test..