Journal article

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

NA Borg, LK Ely, T Beddoe, WA Macdonald, HH Reid, CS Clements, AW Purcell, L Kjer-Nielsen, JJ Miles, SR Burrows, J McCluskey, J Rossjohn

NATURE IMMUNOLOGY | NATURE PUBLISHING GROUP | Published : 2005

DOI: 10.1038/ni1155

University of Melbourne Researchers

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Keywords

Structural Basis
Surface Plasmon Resonance
Antigen Recognition
Complex
Receptors, Antigen, T-Cell
Histocompatibility Antigens
Molecular Sequence Data
Conformational-Changes
Protein Structure, Tertiary
Tcr Binding
Cells, Cultured
Models, Molecular
Cellular Immunology; Immune System and Allergy
Crystal-Structure
Peptides
Complementarity Determining Regions
Science & Technology
Immunology
Thermodynamics
Ligands
Epstein-Barr-Virus
Hot-Spot
Humans
Class-Ii
Mutation
In-Vivo
Kinetics
Base Sequence
Life Sciences & Biomedicine