Salivary cortisol measurements in sick infants: A feasible and objective method of measuring stress?
D Harrison, L Johnston, K Spence, D Gillies, S Nagy
Journal of Neonatal Nursing | Published : 2005
Purpose: To investigate the utility of salivary cortisol as an objective measure of stress in sick infants. Participants: One hundred and forty four infants nursed in two neonatal intensive care units in two children's hospitals in Australia. Design: A prospective observational cohort study. Methods: Infants' saliva was collected using a 3 mL syringe attached to a shortened size 8 FG feeding tube. Salivary cortisol levels were measured using ELISA and examined for associations with potential environmental stressors in the NICU. Main outcome measures: 1.collection of saliva in sufficient volumes for analysis,2.relationship between salivary cortisol levels and environmental factors associated ..View full abstract