Journal article

Temporal lobe epilepsy

RP Carne, TJ O'Brien, CJ Kilpatrick, LR MacGregor, RJ Hicks, MA Murphy, SC Bowden, AH Kaye, MJ Cook

Journal of Neurosurgery | AMER ASSOC NEUROLOGICAL SURGEONS | Published : 2005


Abstract Object. The syndrome of medial temporal lobe epilepsy (MTLE) may occur in patients in whom magnetic resonance (MR) images demonstrate normal findings. In these patients, there is no evidence of hippocampal sclerosis on neuroimaging, and histopathological examination of the resected hippocampus does not reveal significant neuron loss. In this paper the authors describe the distinct clinical features of this MTLE subtype, referred to as paradoxical temporal lobe epilepsy (PTLE). Methods. The authors selected 12 consecutive patients with preoperative findings consistent with MTLE in whom MR imaging did not demonstrate any hippocampal abnormality. Onset of hippocampal seizure was confir..

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