Journal article

Changes in indoor allergen and fungal levels predict changes in asthma activity among young adults

MC Matheson, MJ Abramson, SC Dharmage, AB Forbes, JM Raven, FCK Thien, EH Walters

Clinical and Experimental Allergy | WILEY | Published : 2005

Abstract

BACKGROUND: Exposures to allergens are thought to be important risk factors for asthma. We conducted a longitudinal study of indoor allergen and fungal levels in Melbourne homes between 1996 and 1998 to examine the effect of changes in allergen exposure upon asthma and associated outcomes. METHODS: Participants were visited at home in 1996 (n=485) and 1998 (n=360), when dust and air samples were collected from their bedrooms and assayed for Der p 1, Fel d 1, ergosterol and fungal propagules. Subjects then attended the lung function laboratory to complete a questionnaire, spirometry, methacholine challenge and skin prick testing. The associations between the change in allergen levels and chan..

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