Recognition and optimal management of schizophrenia and related psychoses

Abstract

Schizophrenia continues to remain one of the major unsolved conditions of our time, contributing significantly to causes of disability worldwide. Advances in neuroimaging have demonstrated that schizophrenia appears to be primarily a neurodevelopmental disorder. The dopamine theory of schizophrenia continues to hold sway but interest is growing in the role of other neurotransmitters. Genetic linkage studies continue to suggest that specific chromosomes have a role in the aetiology of the condition but the findings are, as yet, inconsistent. A new generation of drug therapies and reforms of the mental health system have meant that it is now possible to treat the majority of those with this co..