Journal article

Recovery from bispectral index-guided anaesthesia in a large randomized controlled trial of patients at high risk of awareness

K Leslie, PS Myles, A Forbes, MTV Chan, TG Short, SK Swallow

Anaesthesia and Intensive Care | AUSTRALIAN SOC ANAESTHETISTS | Published : 2005

Abstract

Electroencephalographic monitors of anaesthetic depth are reported to assist anaesthetists in reducing recovery times. We explored the effect of bispectral index (BIS) monitoring on recovery times in a double-blind, randomized controlled trial of 2,463 patients at high risk of awareness. Patients were randomized to BIS-guided anaesthesia or routine care. In the BIS group, anaesthesia was adjusted to maintain a BIS value of 40-60 from the commencement of laryngoscopy to the start of wound closure, and 55-70 during wound closure. In the routine care group, anaesthesia was adjusted according to traditional clinical signs. In multivariate models, BIS monitoring, female gender, lower American Soc..

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University of Melbourne Researchers