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Journal article

In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc

DE Hoke, JL Tan, NT Ilaya, JG Culvenor, SJ Smith, AR White, CL Masters, GM Evin

The FEBS Journal | WILEY | Published : 2005

DOI: 10.1111/j.1742-4658.2005.04950.x

University of Melbourne Researchers

Genevieve Evin's Profile Picture
Genevieve Evin Author Clinical Pathology

Colin Masters's Profile Picture
Colin Masters Author Florey Department of Neuroscience and Mental Health

Janetta Culvenor's Profile Picture
Janetta Culvenor Author Clinical Pathology

Related Projects (1)

Project icon

NEURODEGENERATIVE DISEASES OF THE AGING BRAIN: DIAGNOSIS & THERAPY BASED ON THE STUDY OF AGGREAGATED PROTEIN DEPOSITIONS

nan

Grants

Awarded by NIA NIH HHS


Citation metrics

32Web of Science
36Scopus
36Dimensions

Keywords

Amyloid Beta
Gel-Electrophoresis
Escherichia Coli
Membranes
Transgenic Mice
Endopeptidases
Guinea Pigs
Brain
Substrate Specificity
Amyloid Precursor Protein
Protein Binding
Cos Cells
Multiprotein Complexes
Gamma-Secretase
Membrane Proteins
Cell Membrane
Beta
Science & Technology
Life Sciences & Biomedicine
Amyloid Precursor Protein Secretases
Gene Expression
Chlorocebus Aethiops
Molecular Weight
Animals
Amyloid Beta-Protein Precursor
Dimethyl Sulfoxide
Biochemistry & Molecular Biology
Phospholipid-Membranes
Disease
State
Zinc
Alzheimer'S Disease
Notch
Transmembrane Domain
Chromatography, Gel
Protein Processing, Post-Translational
Mutations

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