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Journal article

The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-nitric oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo

R Cappai, F Cheng, GD Ciccotosto, BE Needham, CL Masters, G Multhaup, LA Fransson, K Mani

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2005

DOI: 10.1074/jbc.M409179200

University of Melbourne Researchers

Joe Ciccotosto's Profile Picture
Joe Ciccotosto Author Biochemistry and Pharmacology

Colin Masters's Profile Picture
Colin Masters Author Florey Department of Neuroscience and Mental Health

Roberto Cappai's Profile Picture
Roberto Cappai Author Biochemistry and Pharmacology

Citation metrics

40Web of Science
39Scopus
39Dimensions

Keywords

Copper Levels
Biochemistry & Molecular Biology
Binding Domain
Cells, Cultured
Life Sciences & Biomedicine
Dependent Autocleavage
Heparan Sulfate Proteoglycans
Cell-Free System
Neurons
Neurite Outgrowth
Nitric Oxide
Growth-Factor
Cells
Ascorbic-Acid
Copper
Amyloid Beta-Protein Precursor
Animals
Heparitin Sulfate
Ascorbic Acid
Alzheimer Disease
Beta-Protein
Brain Chemistry
Science & Technology
Secretase
Peptide Fragments
Zinc
Mice, Knockout
Mice
Fibroblasts

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