Journal article

Reduced volume of parietal and frontal association areas in patients with schizophrenia characterized by passivity delusions

P Maruff, SJ Wood, D Velakoulis, DJ Smith, B Soulsby, J Suckling, ET Bullmore, C Pantelis

PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2005

Abstract

BACKGROUND: In patients with schizophrenia, passivity delusions are characterized by a difficulty in determining the agency of purposive actions. Neuropsychological and functional neuroimaging data suggest that passivity delusions are associated with dysfunction of the parietal lobe association cortex. METHOD: Cortical volume calculated from magnetic resonance imaging data in a group of 12 patients with schizophrenia characterized by motor passivity delusions was compared statistically with the cortical volume of 11 patients without passivity delusions. RESULTS: Reduced cortical volume was observed in parietal and frontal association cortices in the passivity group. CONCLUSIONS: These data p..

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