Journal article
Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report
T Naka, D Jones, I Baldwin, N Fealy, S Bates, H Goehl, S Morgera, HH Neumayer, R Bellomo
CRITICAL CARE | BIOMED CENTRAL LTD | Published : 2005
DOI: 10.1186/cc3034
Abstract
OBJECTIVE: To test the ability of a novel super high-flux (SHF) membrane with a larger pore size to clear myoglobin from serum. SETTING: The intensive care unit of a university teaching hospital. SUBJECT: A patient with serotonin syndrome complicated by severe rhabodomyolysis and oliguric acute renal failure. METHOD: Initially continuous veno-venous hemofiltration was performed at 2 l/hour ultrafiltration (UF) with a standard polysulphone 1.4 m2 membrane (cutoff point, 20 kDa), followed by continuous veno-venous hemofiltration with a SHF membrane (cutoff point, 100 kDa) at 2 l/hour UF, then at 3 l/hour UF and then at 4 l/hour UF, in an attempt to clear myoglobin. RESULTS: The myoglobin conce..
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