Maternal 25-hydroxyvitamin D and parathyroid hormone concentrations and offspring birth size

Abstract

Context: There is inconsistent evidence that maternal 25-hydroxyvitamin D [25-(OH)D] deficiency may impair fetal growth. Objective: The objective of the study was to examine the relationship between maternal 25-(OH)D and PTH concentrations at less than 16 and 28 wk gestation and offspring birth size. Design: This was an observational study. Setting: The study was set at a hospital antenatal clinic. Participants: Women with singleton pregnancies, before 16 wk gestation, participated. Interventions: No interventions were used. Main Outcome Measure: Knee-heel length at birth was the main outcome measure. Results: Altogether 374 of 475 (79%) women completed this study. We found no evident relati..