Health-related quality of life and functioning in bipolar disorder: the impact of pharmacotherapy.
Michael Berk, Karen Hallam, Nellie Lucas, Linda Kader, Craig Macneil, Melissa Hasty, Seetal Dodd, Gin Malhi, Philippe Conus
Expert Review of Pharmacoeconomics and Outcomes Research | Published : 2006
Bipolar disorder has a major deleterious impact on many aspects of a patient's functioning and health-related quality of life. Although the formal measurement of these deficits has been neglected until recently, many well-designed trials now include an assessment of functioning and health-related quality of life using one or more rating scales. This review describes recent developments in the measurement of functioning and health-related quality of life in bipolar disorder, and discusses the evidence that medications that improve symptoms in bipolar disorder also offer clinically relevant benefits in functioning and health-related quality of life. Direct comparisons of the benefits of medica..View full abstract