Journal article
Synthesis of 11C labelled methyl esters: Transesterification of enol esters versus BF3 catalysed esterification - A comparative study
U Ackermann, P Blanc, CL Falzon, W Issa, J White, HJ Tochon-Danguy, JI Sachinidis, AM Scott
Radiation Physics and Chemistry | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2006
Abstract
C-11 labelled methyl esters have been synthesized via the transesterification of enol esters in the presence of C-11 methanol and 1,3 dichlorodibutylstannoxane as catalyst. This method leaves functional groups intact and allows access to a wider variety of C-11 labelled methyl esters compared to the BF3 catalysed ester formation, which uses carboxylic acids and C-11 methanol as starting materials. © 2005 Elsevier Ltd. All rights reserved.