Journal article

Oral chlorambucil for extranodal, marginal zone, B-cell lymphoma of mucosa-associated lymphoid tissue of the orbit

Guy J Ben Simon, Ning Cheung, Penny McKelvie, Richard Fox, Alan A McNab

OPHTHALMOLOGY | ELSEVIER SCIENCE INC | Published : 2006

Abstract

PURPOSE: To report the outcome of oral chlorambucil as a single treatment in patients with orbital mucosa-associated lymphoid tissue (MALT) lymphoma. DESIGN: Retrospective nonrandomized clinical study. PARTICIPANTS: Thirty-three patients with isolated orbital MALT lymphoma. METHODS: Medical records of all patients with histology-verified orbital MALT lymphoma treated with oral chlorambucil at the Royal Melbourne Hospital were reviewed. MAIN OUTCOME MEASURES: Complete clinical response, partial response, local relapse, systemic extension (distant relapse), and survival. RESULTS: Thirty-three patients (19 female; mean age, 69 years) participated in the study. Patients received an average of 4 ..

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