Journal article

Patterns of postoperative systemic vascular resistance in a randomized trial of conventional on-pump versus off-pump coronary artery bypass graft surgery

James Tatoulis, Suzanne Rice, Penelope Davis, John C Goldblatt, Silvana Marasco

ANNALS OF THORACIC SURGERY | ELSEVIER SCIENCE INC | Published : 2006

Abstract

BACKGROUND: Off-pump coronary artery bypass grafting (OPCAB) is associated with a less intense systemic inflammatory response according to biochemical markers. We studied systemic vascular resistance (SVR) as a physiologic response to systemic inflammatory response to determine any differences between OPCAB and on-pump coronary artery bypass grafting (ONCAB) in a prospective randomized trial. METHODS: One hundred consecutive patients were randomized to OPCAB or ONCAB, 50 in each group. Antifibrinolytics and steroids were not used. All protocols were identical except for cardiopulmonary bypass. Temperature, SVR index, cardiac index, and blood pressure were measured continuously for the first ..

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