Journal article

Trophoblast and hypoblast in the monotreme, marsupial and eutherian mammal: evolution and origins

L Selwood, MH Johnson

BIOESSAYS | WILEY | Published : 2006


The pregastrula stage mammalian conceptus consists of both embryonic and non-embryonic components. The latter forms the bulk of the tissues, provides nutrition for the developing embryo and also contributes developmental signals that influence events within the embryo itself. Understanding the origins and relationships between the embryonic and extraembryonic cell lineages is thus central to understanding development in mammals. Despite the apparent gross differences in early developmental strategy and form, the conceptuses of eutherian, marsupial and monotreme mammals show some remarkable similarities in the lineage allocation to trophoblast and hypoblast and in the emergent properties of t..

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University of Melbourne Researchers